AstraZeneca

Scientist Cellular Resilience TCAU

US - Waltham - MA Full time

About the role 

At AstraZeneca, we're embarking on an exciting new frontier in medical science – the quest to extend human healthspan. Our newly formed Aging Research Group is at the forefront of this groundbreaking initiative, aiming to develop innovative therapeutics that not only add years to life but life to years.

We are seeking a highly motivated Scientist to join our newly formed, dynamic team. As a key member of our group, you'll play a pivotal role in conducting assays to support drug development of small molecule compounds that support cellular resilience throughout the aging process. At

AstraZeneca, you'll have the opportunity to make a significant impact on the future of healthcare while working in a collaborative environment at the cutting edge of research. The ideal candidate will thrive in this setting, contributing to our growth trajectory as we build our evolving team.   

Key Responsibilities 

  • Design and implement experiments to assess intervention of the cellular aging process, with an emphasis on signaling pathways 

  • Contribute to in vivo experiments assessing the activity of small molecule compounds (preference for those with an understanding of PK/PD parameters) 

  • Analyze and interpret complex experimental data, and present findings to both internal and external stakeholders 

  • Collaborate with cross-functional teams to advance research projects from concept to pre-clinical development 

  • Stay current with scientific literature and emerging technologies in the fields of immunology and aging 

 

Qualifications 

  • Bachelor’s or Master’s degree or equivalent experience with a minimum of 3 years post-graduation research experience, or a PhD with 0 years of experience 

  • Experience in designing, executing, and interpreting cell-based assays  

  • Experience with small molecules 

  • Outstanding communication and interpersonal skills with the ability to build effective relationships in a small team setting  

  • Excellent analytical and problem-solving skills  

 

Desired Skills and Attributes 

  • Understanding of small molecule pharmacokinetics 

  • Self-driven with the ability to work independently and as part of a team  

  • Adaptable and comfortable with changing priorities in a fast-paced research environment  

 

The annual base pay for this position ranges from $87,200 - $130,800. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. 

Date Posted

10-Nov-2025

Closing Date

30-Dec-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.