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This role is based in the Digital Endpoints and Patient-Centered Solutions (DEPCS) team, the innovative digital, AI, and tech function within Roche Product Development Data Sciences (PDD). Operating across the Science of Medicines and Operations, DEPCS is responsible for embedding patient-centered and AI-enabled digital solutions into the fabric of clinical research. By integrating data science, measurement science, and digital product thinking, DEPCS delivers scalable and regulatory-ready innovations that enhance trial design, evidence generation, and clinical value of Roche medicines.
The Imaging Scientist / MD Radiologist plays a central role in advancing imaging science within DEPCS by developing, validating, and guiding the use of imaging-based biomarkers and AI-powered solutions across drug development. With expertise in radiology and medical image interpretation, this role supports the integration of imaging into clinical trial protocols and ensures scientific, technical, and regulatory rigor in imaging applications. Collaborating with cross-functional teams—including data scientists, clinical experts, and biostatisticians—this role shapes how imaging contributes to evidence generation, patient-centric strategies, and therapeutic innovation across TAs.
You provide clinical imaging scientific advice for study/project teams and during interactions with imaging service providers
You contribute to imaging science strategy across disease areas and clinical programs within DEPCS TA Digital Strategy
You develop relationships with cross-functional stakeholders to ensure proactive consideration of imaging strategies during clinical development planning
You employ imaging expertise to answer questions and address issues that arise during ongoing clinical trials, for instance advising on criteria-, modality-, or medical questions raised by medical monitors
You finalize imaging charters (e.g., RECIST or Lugano in oncology) and provide input on additional criteria to add value to the specific protocol
You perform tasks related to image data management, image transfer, and organization
You independently execute analysis of a variety of radiology imaging data (PET, CT, MRI), preferably with AI/ML tools
You identify opportunities and support inclusion of novel automated imaging analysis biomarkers in late-stage clinical trials
You support communications with reading centers and contribute to creation/editing of imaging manuals, imaging review charters/grading protocols, image transfer agreements, etc.
You contribute scientific expertise for novel imaging biomarker development and validation
You support radiologist networks and ensure consistency, quality, and scalability of annotations
You facilitate internal education and innovation around imaging-enabled trial design and analysis
You informally mentor junior team members by leveraging technical experience to build subject matter expertise across the team and professional experience to shape growing leaders
You implement QA of imaging annotations and vendor deliverables in alignment with regulatory expectations
You are a board certified MD with formal radiology training (residency and/or fellowship), 6+ years experience practicing radiology post-training, 2+ years of biotech/pharma/academic experience, or other relevant experience of using imaging in clinical trials
OR
You have a Masters of Science or Masters of Engineering degree with 6+ years of biotech/pharma/academic experience, or other relevant experience of using imaging in clinical trials
OR
You hold a PhD in relevant scientific/engineering discipline preferred with 4+ years of relevant biotech/pharma/academic experience, or other relevant experience of using imaging in clinical trials
You have experience developing and/or using artificial intelligence-based radiology tools
You bring deep expertise in imaging interpretation, imaging-based endpoints, and imaging standards
You have experience leading imaging strategies in support of drug development or regulatory submissions
You have experience with ‘hands-on’ quantitative analysis of imaging data in clinical trials (familiarity with PET, CT, MRI imaging)
You have experience working with MATLAB or Python
You have a good working knowledge of statistics and its applications within the biomedical sciences
You are familiar with clinical trial regulations and Good Clinical Practice (GCP)
You demonstrate capacity for independent thinking and ability to make decisions based upon sound principles
You bring excellent strategic agility including problem-solving and critical thinking skills, and agility that extends beyond the technical domain
You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
You have excellent verbal and written communication skills, specifically in the areas of presentation and writing, with the ability to explain complex technical concepts in clear language
Record of publications or conference presentations related to imaging or AI in medicine
Experience mentoring radiologists or leading imaging review networks
Familiarity with regulatory engagement related to imaging endpoints or tools
Relocation benefits are not available for this posting
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