Pfizer

Manufacturing Supervisor

United States - North Carolina - Sanford Full time

Use Your Power for Purpose

Our breakthroughs would not reach the hands of patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand the critical impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and continuously strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to the medicines they need. 

What You Will Achieve

This role is in Vaccines - Central Solutions Group to support 24/7 Operations. In this role, Manufacturing Supervisor is responsible to lead and develop a production team in a cGMP regulated environment to ensure safe, compliant, and efficient manufacturing operations. The incumbent will drive performance, quality, and continuous improvement while fostering a culture of accountability, teamwork, and data integrity. :

  • Accountable and responsible for leading assigned production staff to achieve targets and deliver and improve process or product consistency, quality/compliance, cost standards and customer service.  

  • Responsible for planning, organizing, staffing, performance assessment, salary recommendations, and employee counseling for a group of employees typically with similar technical responsibilities. 

  • Ensures that work performed by the assigned staff is accurate, timely, efficient, and compliant with corporate policies, plant SOPs, cGMP regulations, and FDA regulations.

  • Participates in investigations and continuous improvement initiatives, applying tools like LEAN manufacturing and Six Sigma to improve quality, cost, safety and/or cycle time. 

  • Collaborates effectively with other functional SMEs to ensure production goals are met and investigations are accurate and complete.  

  • Has a basic understanding of product cost structure, budgeting process, and spending. 

  • Optimizes resources to maximize production and ensure quality and safety standards.

  • Focuses on Safety and GMP Compliance as operational priorities and as performance measures that should be included in metrics.

  • Knows the processes and procedures, including the principles and practices of good data management (ALCOA), and be able to guide, advise, and coach their teams.

  • Holds recurring conversations with team to solicit feedback and identify ways to promote a culture of procedural compliance and strong data management practices.

  • Ensures a safe work environment. Ability to identify, evaluate, and correct potential hazards in the workplace is essential.

  • Coordinates, schedules, and participates in daily activities of cGMP production in the manufacturing area to meet supply chain needs.

  • Must be flexible to work rotating shifts to support 24/7 operation.

  • Ensures that product quality is maintained through all phases of commercial and clinical production including operational parameters of manufacturing equipment, personnel activities, batch record/processing dynamics, and integrated utilities to identify and resolve quality risk to commercial and clinical manufacturing. General knowledge of scientific principles, production equipment and related procedures. 

  • Aids in investigations. Responsible for the adherence to established policies, procedures, and practices. Participates in site inspections and cGMP and Quality decisions effecting short term production

  • Provides supervision to direct reports. Motivates personnel by setting high standards, encourage teamwork; clear, unambiguous communication is critical.

  • Primary contact for all personnel issues occurring with their direct reports. Responsible for development plans and personnel reviews. Makes initial decisions encompassing personnel issues, disciplinary actions, career advancement, educational assistance, Emergency situations, including injured employees, facility issues, and inclement weather.

  • Reviews completed batch records. Supports the development of training material, update curricula, close training gaps, support the training of new supervisors/operators.

  • Advises management of non-conformance issues and opportunities for continuous improvement

  • Provides input on primary decisions on cGMP related documents developed or revised.

  •  Articulates challenges and solutions to technical and non-technical peers and to department   management.

  •  Provides technical guidance and act as a departmental liaison with primary support groups.

  •  Responsible for short range planning (scheduling daily and weekly operations and staff) and longer range planning (facilities shutdowns and preventive maintenance).

Here Is What You Need (Minimum Requirements)

  • Applicant must have a bachelor's degree with at least 2 years of experience; OR a master's degree with 0+ years of experience;
    OR an associate's degree with 6 years of experience; OR a high school diploma (or equivalent) and 8 years of relevant experience

  • Strong people management skills.

  • Ability to identify, evaluate, and correct potential hazards in the workplace.

  • Experience in pharmaceutical manufacturing or a related field.

  • Knowledge of current Good Manufacturing Practices (cGMP).

  • Proficiency in managing quality, compliance, and customer service.

Bonus Points If You Have (Preferred Requirements)

  • General knowledge of scientific principles.

  • In depth knowledge of biopharmaceutical unit operations.

  • Experience with production equipment and related procedures.

  • Experience in process improvement and innovation.

  • Ability to work collaboratively with cross-functional teams.

  • Previous Leadership, Supervisory or management experience is preferred.

PHYSICAL/MENTAL REQUIREMENTS

  • Working knowledge of vaccine or biotechnology product manufacturing in a cGMP environment. Including a working knowledge of fermentation, purification, centrifugation, Fermentation/Cell Culture, Purification, Conjugation, Solution Prep and Aseptic Filling of Various expression system processes (ie. Bacterial, viral and mammalian cells), aseptic techniques and other filtration processes.

  • Optimize resources to maximize production and ensure quality and safety standards.

  • Moderate repetitive standing, sitting, bending, ladder climbing, pushing and lifting (up to 40lbs) required on a daily basis. 

  • Ability to perform mathematical calculations and learn new processes/systems.

  • Strong problem-solving skills and the ability to manage complex projects.

  • Strong leadership and collaboration capabilities.

  • Aseptic gowning required on manufacturing floor.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Two positions are 12 hour Day Shift (Rotation of 3, 2, 2 schedule)

Two positions are 12 hour Night Shift (Rotation of 3, 2, 2 schedule)

OTHER JOB DETAILS

Last Date to Apply for Job: Nov 13, 2025.

Referral Bonus Eligibility: YES

Eligible for Relocation Package: NO


Work Location Assignment: On Premise

The annual base salary for this position ranges from $80 300,00 to $133 900,00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 10,0% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

Manufacturing