Company Background

Are you an experienced Marketing Professional looking to be part of a company that follows the science and turns ideas into life changing medicines? If you are passionate about what science can do to make a difference to patients' lives and ready to discover what you can do – join us.  

Our ambition is to improve and save lives for the millions of people who are living with the complexities of Cardiovascular, Renal & Metabolic (CVRM) diseases. AstraZeneca is uniquely positioned to improve the outcomes of patients living with CVRM diseases today and tomorrow with our strong and expanding portfolio and one of the broadest, deepest, most innovative pipelines in the industry. By 2032, we intend to be leading the world in CVRM therapies, launching up to fifteen (15) new life-changing medicines.  

To support this ambition, we are seeking an experienced commercial leader to accelerate the commercial development of our oral PCSK9i asset as well as work closely with the oral PCSK9i/FDC Global Marketing Head, and our oral PCSK9i asset fixed-dose combinations across CVRM indications to shape the future of dyslipidemia and prepare the organization for outstanding global launches.

The Global Commercial Head oral PCSK9i will report to the Global Commercial Vice President, oral PCSK9i.

Job overview:

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. Working here means being

This role reports directly to the Vice President, oral PCSK9i asset and will be expected to have a high level of collaboration with global cross functional groups (Patient & Business Insight, Medical Affairs, R&D, Pricing & Market Access, Commercial Excellence, Customer Advocacy and Congresses, etc) and local Market Company (MC) teams. In this role, you will be accountable to evolve the strategic plan, execute the operational plan, and provide launch preparation support to key launch countries. The successful candidate must be a strong matrix leader and global commercial leader, with specific responsibility for shaping and implementing brand strategy. Clear thinking with the ability to lead and demonstrate passion for the brand is required.

What you’ll do:

Develop and Execute Global Marketing Strategy

• Create clear, effective marketing plans for oral PCSK9i asset, focusing on patient needs and market insights.
• Work with key regions (including the USA) to ensure the strategy is carried out and launches are successful.

Lead Brand and Indication Planning:

• Use feedback from important markets to shape the brand’s positioning, target audience, and value proposition.
• Collaborate with cross functional teams such as Medical, Pricing, Regulatory, and R&D to devise strategic and operational plans for all markets.
• Head the oral PCSK9i asset commercial sub-team and represent the commercial perspective in decision-making forums.

Customer and Market Insights:

• Gather and use customer and market data to guide clinical development and regulatory plans.
• Build a plan to address key business inquiries & opportunities to inform and shape brand strategies.

Oversee Revenue Forecasts and Business Cases:

• Ensure revenue forecasts and business plans are future proofed and based on solid customer insights, product strengths, competitive positioning, unmet need and pricing & market access.

Engage & Collaborate with Internal & External Stakeholders:

• Collaborate and partner with disease experts and policy makers to represent customer and patient perspectives.
• Lead discussions with healthcare professionals at advisory boards and conferences.
• Identify and lead relationships with strategic marketing agencies, vendors, consultants, and other third-party groups.
• Collaborate with members of the AVSCD commercial team to shape portfolio and disease area strategy.
• Lead the multi-disciplinary effort to create differentiated target product profiles (TPPs) that are validated with insights from external experts and/or key customer groups.
• Head the oral PCSK9i asset commercial sub-team and represent the commercial perspective in decision-making forums.

Shape Team Culture and Develop Talent:

• Create an employee experience that ignites innovation and unites talent to deliver the business. Lead and align team around a clear vision and purpose. Role model AZ Values and champion AZ’s people strategy by attracting, developing, and retaining talent while building a diverse pipeline of future Commercial leaders.

Size of Team:

• The Head of oral PCSK9i asset will oversee 2 direct reports, both global Marketing Directors.

Industry/Functional Experience

Required:

• BA/BS in Business, Medical or Life sciences is required

• Deep CVRM expertise and experience, with broad US/Global professional relationships with Key External Experts in CVRM therapy areas

• 15+ years’ experience in pharmaceutical development and commercialization including at the Global level
• Commercial/ marketing role in US with launch experience

• Demonstrated success leading and developing global multi-disciplinary teams
• Experience leveraging clinical data to shape brand strategies and lifecycle planning

• Solid understanding of forecasting, market research, useful insight generation, and competitive landscape analysis and interpretation
• Advanced internal and external partner engagement skills with demonstrated ability to seamlessly navigate scientific and commercial organizations to drive business outcomes
• Strong analytical, organizational and communication/presentation skills (written and verbal)
• Demonstrated ability to collaborate and influence laterally and vertically with senior leadership and cross functional stakeholders.
• Scientific curiosity

Desirable:

• Advanced degree (MBA or PhD) in life science and/or business management
• US/Global professional relationships with Key External Experts in Cardiology

Next Steps – Apply Today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

The annual base pay for this position ranges from $270,221 to $405,332. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

Date Posted

06-Nov-2025

Closing Date

27-Nov-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.