Lilly

Associate, Portfolio Management Enablement &Transformation

US, Indianapolis IN Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview: 

Portfolio Management Strategy and Capabilities (PMSC), as part of Portfolio Project Management (PPM), leads the strategic direction, creates forward-looking capabilities, and supports a collaborative culture to enable the PPM organization to speed the delivery of medicines to patients globally. PMSC is responsible for creating and right-sizing processes and technologies to streamline work and facilitate portfolio planning and decision making; training and onboarding staff; and driving transformational initiatives to ensure PPM capabilities lead the industry. R&D project management plays an important role in leading drug development programs and advising leadership on portfolio performance. Development teams, portfolio managers, and business functions utilize information from portfolio systems (Prism Live, Polaris, Prism Data Layer, and Prism Reporting) to manage project and portfolio performance, support decision making at both a portfolio and project level, and resource planning. Portfolio Management & Enablement (PMET)- Portfolio Systems is responsible for managing the administration of portfolio systems, delivery of portfolio data to the organization via standard datasets and reports and adapting systems and tools to meet emerging business needs in partnership with Tech@Lilly, PMET-Resource Modeling and Forecasting (RMF), the Project Management Office (PMO), Finance, and HR.

Primary Responsibilities:

As an Associate, Sr. Associate, and Manager (P1-3) in PMET-Portfolio Systems, you will play a key role in supporting the daily operations and administration of enterprise portfolio systems that enable R&D project management and strategic decision-making. You will collaborate closely with cross-functional teams including Tech@Lilly, PMET-RMF, the PMO, and vendor partners to ensure accurate data delivery, system stability, and continuous improvement. Your contributions will help drive portfolio performance tracking, resource planning, and reporting, supporting both project-level execution and enterprise-wide investment analysis. With each level, your leadership in system strategy and enterprise initiatives grows, enhancing portfolio oversight and business value.

System Administration and Configuration Management

  • Serve as subject matter expert on Prism Live functionality, configuration, data standards, templates, activity libraries, resources, and forecasting algorithms within Prism Live.

  • Enable continuous improvement to PM Systems by contributing to robust technical requirements, validation plans, and acceptance testing criteria for changes to the system.

  • Foster and maintain a strong rapport with Prism Live support (Tech@Lilly and vendor).

  • Support documentation on Prism Live administrative tasks, including system configuration, system functionality, forecasting algorithms, vendor service requests, batch management, system interfaces, user management, release management, and testing.

  • Assist in coordination of system communications (e.g. configuration changes, data changes, process changes) with Portfolio Operations and Business Planning (POBP), PMO, PMET-RMF, and PM Leadership.

  • Ensure, in partnership with PMO and Tech@Lilly, that proper access and security measures are in place and in alignment with Protect Lilly frameworks. This includes access approvals, roster reviews and subscription renewals, PowerBI data access, and maintenance of Prism Security documentation.

Portfolio Reporting and Data Management

  • Foster and maintain a strong rapport with Prism report developers and portfolio data consumers (within Tech@Lilly, PMET-RMF, Finance, POBP, and Decision Science).

  • Coordinate with Tech@Lilly on business-driven changes to downstream portfolio data models, PowerBI reporting datasets, or materialized views for portfolio reporting.

  • Work closely with reporting SMEs to understand emerging business needs for portfolio reporting and analytics.

  • Support key data integrations with portfolio systems, including Workday, Vault Clinical, and SAP.

Shared Learning and Process Improvements

  • Support 'continuous improvement' initiatives to simplify and streamline processes, including those which are functional and PM cross-functional in nature.

  • Identify, share, and incorporate best practices into future iterations of processes, tools, and training

  • Participate in portfolio systems strategy and road mapping exercises with both Tech@Lilly and vendor support.

  • Demonstrate independent problem solving.

  • Lead through change effectively, including understanding.

Basic Requirements: 

  • Bachelor’s degree in Computer Science, Information Technology or related technical/scientific field.

  • 3+ years of work experience in the pharmaceutical industry and/or drug development.

  • Experience working through formal IT/system change management processes.

  • Experience with enterprise project management software (e.g., Planisware, Critical Chain, Planview)

  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.

Additional Skills/Preferences:

  • Data analysis experience and technical skills (e.g., SQL/NoSQL, PowerBI, PowerQuery, R, Python).

  • Strong interpersonal and teambuilding skills; able to develop effective teamwork and deliver coaching and feedback.

  • Strong critical thinking and problem-solving skills; able to anticipate and recognize issues, diagnose root causes, and propose creative alternatives.

  • Understanding of and expertise in IT terminology and systems.

  • Demonstrated good oral and written communication skills; able to organize messages succinctly and clearly for multiple levels within the organization.

  • Demonstrated ability to learn quickly and perform new work tasks as directed.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$65,250 - $148,500

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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