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Takeda Biotherapeutics Process Development (BPD) supports cutting edge modalities, including mAbs, mAb fusion, bispecific antibodies, bioconjugates and the enzyme replacement therapies, targeting oncology, gastrointestinal tract disorders, neurological diseases, and rare diseases. As a major function of BPD, the Cell Line Development (CLD) team creates production cell lines and generate cell banks through the application of great science and technologies. The performance of CLD ensures a reliable cell supply for drug substance production, which is used for clinical and commercial biotherapeutic products.
How You Will Contribute:
As a Cell Line Development Data Science Intern, you will have the opportunity to…
Build a bioinformatics workflow to detect indel mutations using simulated and experimental NGS datasets. The tool will be useful for detecting sequence variants and gene knockout clones.
Optimize and test structure variant detection scripts.
Build a pipeline of analyzing TLA-NGS datasets to identify integration sites of production cell lines.
Support the team to explore the possibility of using machine learning tools to optimize expression constructs and predict genetic and phenotypic stability.
Internship Development Opportunities:
The intern will gain insights into the CLD workflow and understand the real-world questions.
The intern will learn and practice the approaches to solving real-world problems in biotherapeutic drug development.
The intern will take the initiative to support the implementation of AI tools in process development.
Job Requirements:
This position will be Hybrid (1-3 days/week in office) out of the Cambridge, MA location
Must be pursuing a Master or Doctoral Degree in data science, biostatistics, bioinformatics, or a relevant field.
A strong background in data science and scientific programing (R/Python)
In-depth knowledge of bioinformatics tools commonly used in NGS data analysis, including BWA, STAR, GATK, samtools, etc. Familiarity with high-performance computing environments (HPC).
Understanding of molecular biology and genetics is highly desired.
Knowledge in AI and machine learning tools is a plus.
Internship Eligibility 
Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship
Must be currently enrolled in a degree program graduating December 2026 or later
The internship program is 10-12 weeks depending on the two start dates (May 26th-August 14th or June 15th- August 21st)
The intern must be able to commit to one of these time frames
Able to work full time 40 hours a week during internship dates
Takeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program
Program Highlights:
Hands-on experience with real projects and responsibilities
Dedicated mentorship program pairing interns with experienced professionals
Networking opportunities with industry professionals and fellow interns
Internship events focused on professional and skills development
Exposure to multiple business areas or departments within a Pharmaceutical Organization
Applications will be accepted between October 31st- November 16th
Takeda Compensation and Benefits Summary
We understand compensation may be an important factor as you consider an internship opportunity. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - MA - Cambridge - Binney StU.S. Hourly Wage Range:
$21.00 - $46.00
The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate’s school year/level to be entered following completion of internship. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. internship benefits vary by location and may include:
Paid sick time
Civic Duty paid time off
Participation at company volunteer events
Participation at company sponsored special events
Access to on-site fitness center (where available)
Commuter Benefit: To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Job Exempt
NoIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.